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Cobalt Allergy and Vitamin B12: What Patients Need to Know What if the very supplement you rely on for energy and vitality is secretly causing your discomfort

The small studies on knee pain and bladder pain are interesting, but they involved fewer than 30 patients total

High-dose supplementationparticularly intramuscular injections that can deliver 1,000 micrograms or morecreates substantially elevated serum B12 levels compared to dietary intake, which may more readily trigger these bacterial changes, though comparative studies between different forms are limited

There is no preservative, and so it cannot be stored