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But the benefits go far beyond the immune system
Furthermore, the oral administration of probiotics increases Akkermansia abundance at 3 days in SBI rat (in the supplementary results) ( Akkermansia significantly increases in ischemic stroke patients ( Akkermansia decreases in stroke patients and radiation-induced brain injury mice ( Akkermansia abundance, and supplementing the diet with the Akkermansia protects against the cognition impairment ( Akkermansia abundance was noteworthy down-regulated after TBI mice, which was different from some previous reports and may be due to difference of design and method, as well as the differences of individual animals, fecal sample collection time and feeding environment in this study
Systemic inflammation, often observed in PD patients, can exacerbate neuroinflammation through the infiltration of peripheral immune cells into the brain, further amplifying the inflammatory response (Li et al