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2002 Aug;77(8):754-9

Mechanism of Action When vitamin B12 is injected, it enters the bloodstream directly, allowing it to be transported to various tissues and organs where it is needed

Published literature going back decades doesn't show significant adverse effects at typical doses

The physical interactions between mitochondria and lysosomes play a critical regulatory role in cell division dynamics, Ca 2+ /nutrient signaling, and selective autophagy processes [112, 318]