Its job is to stimulate insulin (which brings glucose into cells, and is why GLP-1 drugs were initially approved as medications for diabetes), and inhibit glucagon (glucagon increases blood sugar and fatty acids in the blood when food isnt present)
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Jamie Bennett, a spokesperson for Wegovy and Ozempic maker Novo Nordisk, declined to comment on the concept of deprescription, noting that its drugs are intended for chronic conditions
Front Endocrinol (Lausanne) (2018) 9:672
It is found that EX can reverse the damage of renal tubular epithelial cells caused by a high-fat diet, and its effect is applied to simvastatin by reversing the down-regulation of SIRT1, preventing the production of reactive oxygen species and inhibiting the apoptosis of mitochondria (50)