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Description

NSAIDs inhibit cyclooxygenase enzymes, reducing prostaglandin synthesis in the gastric mucosa and impairing the mucous layer that protects against acid

Finally, TRANSCEND-T2D-3 (NCT06297603) will compare retatrutide to placebo over 14 months, in people with inadequately controlled T2D and moderate-or-severe renal impairment on basal insulin

Genetically predicted higher l-carnitine was associated with lower HDL-cholesterol in men (effect size 0.04, 95% CI 0.06 to 0.02), and not in women (0.004, 95% CI 0.05 to 0.06, p value=0.88)