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Epidemiological studies linking GLP-1 use to lower dementia risk are vulnerable to confounding, because the people prescribed these drugs differ in many ways from those who are not

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GLP-1 stimulation in a severely compromised pancreas might paradoxically worsen symptoms or trigger acute flares rather than improve metabolic health

Patients go in knowing the rules exist, but not exactly how theyre being measured against them

2013;8(12):e83084