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doi: 10.1073/pnas.1219451110 72 WangLLiPTangZYanXFengB

The American Diabetes Association (ADA) guidelines recommend GLP-1 receptor agonists as preferred agents for patients with type 2 diabetes and atherosclerotic cardiovascular disease, while SGLT2 inhibitors are preferred for heart failure and chronic kidney disease

Other serious side effects include increased blood pressure and heart rate and, less commonly, liver damage or hepatitis, vision problems, increased risk of low blood sugar in people with type 2 diabetes, or manic episodes

Clinical trials demonstrate that patients receiving liraglutide showed 18% slower cognitive decline over one year compared to placebo 30