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When cytosolic copper rises, the Cu-ATPases ATP7A and ATP7B translocate from the trans-Golgi network (TGN) to the plasma membrane and pump the surplus copper out of the cell

Surgical Procedures: Endoscopic Pyloromyotomy (G-POEM): A newer endoscopic procedure where a cut is made in the pyloric muscle (the ring between the stomach and small intestine) to open the channel and improve stomach emptying

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DNP Originally used in the manufacture of explosives in World War I, and subsequently in fungicides, insecticides and photographic development (McVeigh et al, 2016) 2,4-Dinitrophenol (DNP) also has an extensive history as a weight loss drug