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NICE has issued technology appraisals for semaglutide 2.4 mg (Wegovy) for weight management (TA875) and for tirzepatide (Mounjaro) for managing overweight and obesity , each with defined eligibility criteria

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Active pancreatitis or history of recurrent pancreatitis is a contraindication for semaglutide and tirzepatide

For convenience, we limited this supplementary search to semaglutide after observing that all businesses identified in the first search and advertising a specific GLP-1 product advertised at least semaglutide

The pharmacotherapies for obesity are directed at the following: 1) decreasing energy intake (e.g