retatrutide side effects trial results VisualAbstract: reduces body weight by 17.5% in patients with obesity retatrutide side effects trial results

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In obese subjects without diabetes, SGLT2 inhibitors do not alter the estimated glomerular filtration rate or have any adverse event potentially related to renal impairment or renal failure over a 52-week period [21]

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It demonstrated a 14% reduction in major cardiovascular events and a 26% reduction in heart attacks specifically for Asian patients.[19] The kidney story gained momentum with the FLOW trial, the first dedicated kidney outcomes study of a GLP-1 medicine

The post says significant weight loss and improved metabolic function may require TSH rechecking and a possible adjustment to thyroid replacement therapy