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Take over-the-counter medications to relieve pain and itchiness If the injection has caused some pain, you can take over-the-counter (OTC) pain relievers, such as acetaminophen (Tylenol) or ibuprofen (Advil and Motrin) for relief

The maintenance trial (NCT06859268) tests whether patients can reduce their retatrutide dose after achieving significant weight loss

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Amino acids can reduce muscle inflammation, suppress pain, help synthesize norepinephrine and dopamine (the brains happy chemicals), and increase blood flow

Patients on immunosuppressive medications (5-ASAs, azathioprine, biologics like infliximab) can generally use GLP-1s concurrently, though each combination warrants provider review