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At the molecular level, astaxanthin upregulates synaptic proteins involved in both pre- and postsynaptic function, such as synaptophysin, PSD-95, and SNAP-25, while promoting neurotrophic signaling through the BDNF/TrkBCREB pathway

The mean absolute bioavailability following intramuscular injection was approximately 14-19% in rats and 45-51% in beagle dogs, suggesting species-specific absorption characteristics relevant for dose translation to human applications

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Furthermore, the complexity of plant biochemistry presents challenges in standardizing and replicating effective active compounds for mass production

Alteration in the chloroplastic metabolism leads to ROS accumulation in pea plants in response to plum pox virus