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Over time, most patients report that the initial side effects resolve while the beneficial effects on appetite regulation persist

The relationship between the bloodbrain-barrier and the central effects of glucagon-like peptide-1 receptor agonists and sodiumglucose cotransporter-2 inhibitors

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In addition, research has shown that the absence of Nrf2 leads to the downregulation of vesicle-associated membrane protein 8, causing ferritin autophagy and the accumulation of nuclear receptor coactivator 4/apoferritin autophagosomes, which regulate ferritin synthesis and degradation, increasing LIP and thereby increasing susceptibility to ferroptosis [126]

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