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Many of these side effect can be reduced by using a lower concentration of steroid solution and spreading it out evenly over the area with multiple injections of small volumes, using a very fine syringe

In this study, we found that proline was increased significantly under the HT treatment and even more when imposed in the HT+GSH treatment

PMID: 19668473

If you use the product in high concentrations or overuse it, it can make these effects worse