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For medical use, see Cyanocobalamin injection for adverse effects and precautions

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In D-galactose-induced aging mice, oral administration of the product significantly increased NAD+ levels in liver and adipose tissue, activated mitochondrial energy metabolism pathways, improved insulin sensitivity, lowered blood glucose and lipid levels, reduced visceral fat accumulation, and increased energy expenditure, alleviating fatigue and abnormal body weight associated with aging

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Furthermore, some people may experience a reddish colour of urine: this is a natural phenomenon as vitamin B12 contains cobalt