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doi: 10.3389/fimmu.2024.1365554 107 WeissG.RasmussenS.Nielsen FinkL.JarmerH.Nhr NielsenB.FrkiaerH

It means that excess positive charge may trigger membrane lysis at increased peptide dosing

Phase 2 data showed weight loss around 24% at 48 weeks, but retatrutide is still earlier in development