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Discontinuation rates from the phase 2 trial due to side effects were generally low, though the broader literature on GLP-1 receptor agonists notes that discontinuation rates across the class can reach 20-50% within the first year

Key Benefits: Enhances fatty acid oxidation Increases skeletal muscle mitochondrial biogenesis Improves endurance capacity Reduces fat mass while preserving lean mass Decreases systemic inflammation In animal studies, SLU-PP-332 activated PPAR similarly to exercisewithout requiring exercise itself