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A 2013 review in Aging Cell showed that declining systemic IGF-1 correlates with reduced dermal collagen density and skin elasticity in adults over 60

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Patients taking CGRP-blocking medications who sustain a fracture may face increased risk of healing complications, though this has not yet been studied systematically

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It should be noted that there are also smaller repulsive forces between molecules that increase rapidly at very small intermolecular distances

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4 Kawcak CE, Frisbie DD, Trotter GW, et al

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