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Benzodiazepine overdose reversal (intentional or iatrogenic)

Lower concentrations or more stable, buffered forms of the vitamin are usually more effective and less irritating for the mouth area

Aebi, H

Notably, Proteobacteria (Pseudomonadota) harboring the phenylpyruvate decarboxylase (PPDC) gene are regarded as the primary contributors to PAGln production in patients with Crohns disease (CD) (124)

Serious but rare adverse effects include pancreatitis, gallbladder disease, acute kidney injury (usually secondary to dehydration from gastrointestinal symptoms), and hypoglycemia when combined with insulin or sulfonylureas