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Improved well-being is often a result of losing weight, leading to increased energy levels, enhanced self-confidence, and a diminished risk of obesity-related health issues

Studies show B12 deficiency can make anemia worse, so supplements could be helpful

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Medications with narrow therapeutic windows, such as warfarin, digoxin, or certain antiepileptic drugs, may require more frequent monitoring when tirzepatide is initiated, as delayed gastric emptying could affect absorption rates and peak concentration timing

Importantly, orlistat is contraindicated in patients with chronic malabsorption syndrome and cholestasis [65], conditions that require avoidance of fatty foods