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Drug development continues to face marked inefficiencies, with approximately 90% of drug candidates failing to reach approval despite extensive preclinical testing ( in vitro models, although cost-effective and suitable for high-throughput studies, lack the architectural complexity and biochemical microenvironment of human tissues

duration = 220 weeks

50 This modest effect was not associated with adverse cardiovascular outcomes in any of the major clinical trials

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Understanding what to expect may help people use these drugs more easily and confidently