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The NICE Clinical Knowledge Summary for vitamin B12 deficiency outlines specific treatment schedules: for patients without neurological symptoms, hydroxocobalamin 1 mg intramuscularly three times a week for 2 weeks

The company backed its application with results from the Phase II/III QUILT-3.032 study, in which maintenance treatment with Anktiva plus BCG elicited a complete response rate of 62%, with duration of response exceeding 47 months at the November 2023 cut-off

G2/M cell cycle arrest and downregulation of Nf-kB/m-TOR/PI3K/AKT pathway

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