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The primary focus of this combination in a research context is the modulation of lipid metabolism, particularly within hepatocytes, through synergistic effects on methylation, signal transduction, and lipoprotein assembly

Importantly, the oral doses (used for daily administration) are those that fall in range of limited tolerability being reported in VENTURE Phase 2 oral study

Adding alcohol to an already compromised gastrointestinal state risks dehydration, electrolyte imbalances, and potential medication discontinuation

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