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The available safety data to support the EUA include an analysis of 30,351 participants enrolled in an ongoing randomized, placebo-controlled study conducted in the U.S

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Treating a B12 deficiency is crucial since a severe deficiency can lead to nerve damage or neurological problems

Reference: Aminian, A., Gasoyan, H., Zajichek, A., Alavi, M

In fact, lower IRRs were observed during both the initial (012 months) and late (1324 months) exposed periods compared with pretreatment, a pattern also seen for SGLT-2 and DPP-4 inhibitors, possibly reflecting increased healthcare contact or a healthier lifestyle during treatment