POMC mRNA transcription in corticotrophs is negatively regulated by glucocorticoids (25), although glucocorticoids increase expression of POMC in the hypothalamus (26)
Acknowledgements This study was supported by a grant from the Chung Shan Medical University (CSMU-INT-101-09), Taiwan
Ekstrom K, Carlsson-Skwirut C, Ritzen EM, Bang P: Insulin-like growth factor-I and insulin-like growth factor binding protein-3 cotreatment versus insulin-like growth factor-I alone in two brothers with growth hormone insensitivity syndrome: effects on insulin sensitivity, body composition and linear growth
[DOI] [Google Scholar] Kaczmarek H, Kaminska A, Swiatek M, Sanyal S
Weight Loss-Independent Effect of Liraglutide on Insulin Sensitivity in Individuals with Obesity and Pre-Diabetes