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Clinical Cancer Research 31(8):1437-1448, 2025

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Because levels of TMAO in the blood are strongly linked to dietary intake, dietary modifications can be a significant way to reduce risk. Because the metabolism of white meat, seafood, dairy and plant-based proteins, in particular, leads to less production of TMAO, they should comprise the majority of your protein sources

The findings of another prospective study (the Hordaland Health Study) that followed 7,045 healthy adults (ages, 47-49 years and 71-74 years) suggested that high choline and low betaine plasma concentrations were associated with an unfavorable cardiovascular risk profile (51)

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