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As only one patient with IIH-WOP was treated with a GLP-1-RA, this was insufficient to conduct subgroup analyses, so we could only perform sensitivity analyses removing IIH-WOP patients to exclude potential confounding effect on our results

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The length of ICU stays and the need for endotracheal intubation in the LC group were significantly less than in the control group ( P 0.05, Table 1)

This requires timing: the new formulation must reach patients at scale before generic entry in the base product erodes the price umbrella that makes the migration commercially viable