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Ethics declarations Competing interests The authors declare that they have no conflict of interest

Skin concerns: Uneven skin tone, dullness, loss of elasticity, dehydration, and barrier sensitivity

The presence of copper may be central to these observations, including collagen synthesis, modulation of inflammatory signaling, and antioxidant potential

This could eventually help reduce reliance on biopsies, which are invasive and difficult to repeat, and make it easier for clinicians to monitor patients over time