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Adjust Diabetes Diet: Do not take foods with much sugar or carbohydrates in the evening before going to bed

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These cytokines activate the nuclear factor kappa-B (NF-B) signaling pathway,inducing the upregulation of apoptotic proteins and matrix-degrading enzymes, such as metalloproteinases (MMPs), which irreversibly degrade the extracellular matrix (ECM) 6,7

Because of this, many doctors recommend combining therapies to address different parts of the problem at the same time