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Cardiovascular outcome trials, once considered ancillary, can strategically reposition metabolic drugs as cardioprotective agents

For example, the weight-loss supplement ephedra was banned in 2004 only after reports of serious side effects, including heart attacks and induced psychosis, some even resulting in death

1-2 hours: Effects developing

[DOI] [PMC free article] [PubMed] [Google Scholar] 144.Huang K.P., Acosta A.A., Ghidewon M.Y., McKnight A.D., Almeida M.S., Nyema N.T., et al

Valsa Mali pathogenic effector vmPxE1 contributes to full virulence and interacts with the host peroxidase mdAPX1 as a potential target