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Trial data have shown weight reductions of up to approximately 22% in clinical studies

Not everyone who experiences a Chronic Illness will have MCAS, but it is estimated that 50% of people with Chronic Illness have MCAS or histamine intolerance and therefore it can be common territory for those with chronic fatigue, post-viral fatigue, long covid or other energy limiting illness

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45 Similarly, previous studies showed that caloric restriction with or without aerobic training improved peak VO 2 in obese elderly HFpEF patients