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Despite being derived from a stress hormone (ACTH), it does not raise cortisol levels

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However, the term Metabolic Syndrome has become commonly used since its inception by the Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) in 2001 [1]

This selective profile is the point it targets fat metabolism without systemic hormonal consequences

Pregnenolone has inhibitory effects on GABA pathways, that when combined with its positive effects on NMDA receptors, provides a feeling of alertness, higher mental clarity, and a sense of wellbeing