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Important things to keep in mind include: Serum B12 levels should be normal for most people Methylmalonic acid (MMA) and homocysteine levels can show if B12 is really working, even if levels seem fine How symptoms change is also important When and How to Adjust Dosing Regimens Doctors might need to change the dose based on test results and how the patient is doing

- Cyanocobalamin must be converted before your body can use it, and not everyone completes this step effectively

methylcobalamin, the adenosyl ligand in vitamin B 12 is replaced by methyl

Subcutaneous B12 injections are a better choice when possible, and the front of the thigh is also best for this method