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Immunoassay Tear fluid was extracted from half of the remaining strip by agitating small cut pieces of these strips in 100 L PBS, Tween20 0.05% and cOmplete Protease Inhibitor Cocktail (Roche, Basel, Switzerland) at 4 C for 1.5 h 28

To date, various published data on PD have explored the role of UA in its pathogenesis

In 2014, a paper in the *Journal of Pharmacology and Experimental Therapeutics* laid out dihexa's proposed mechanism that it works by binding hepatocyte growth factor and activating the c-Met system to build synapses

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