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GLP-1 medications like semaglutide and tirzepatide most commonly cause gastrointestinal side effects, particularly nausea, vomiting, and constipation, especially during dose escalation

If youve had a chronic, severe vitamin deficiency for many years, your symptoms will be more significant than they would be after a few weeks of decreased B12 intake

Medical devices In some instances, medical devices such as pessaries or urethral inserts can be used to provide support and alleviate symptoms

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A 2025 Kinsey study showed that 18% of respondents said their sexual desire had increased on GLP-1s while 16% said it had decreased