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Tsokos GC, Lo MS, Costa Reis P, Sullivan KE (2016) New insights into the immunopathogenesis of systemic lupus erythematosus

Hepatocellular enlargement or swelling may occur from accumulation of glycogen, fat, or other substances and may also be a feature of degeneration and some forms of hepatocellular necrosis

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However, it seems to have negated the increases in cavernosal pressure that melanocortin agonists potentially induced

This precaution aims to minimize the risk of aspiration and related complications