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Oberholzer HM, van der Schoor C, Bester MJ (2015) Sibutramine, a serotoninnorepinephrine reuptake inhibitor, causes fibrosis in rats

The hepatic fat-areas were initially manually annotated on a high number of sections, thereby teaching the machine learning algorithm how to distinguish these two areas, hepatic cells with single droplets (macrovesicular) and hepatocytes included multiple small droplets (microvesicular), from background such as vessels and artefacts

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Shifting Melanin Production Not only does glutathione inhibit melanin production, but it also promotes the conversion of eumelanin (the darker pigment) to pheomelanin (the lighter pigment)