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Lipoxygenase converts free PUFA into lipid oxides, which significantly affects iron redox reactions (Yang et al., 2016)

It says the intended mechanism is enhanced carnitine-dependent fatty acid oxidation and methyl-donor metabolism

Hardt K, Vandebosch A, Sadoff J, Le Gars M, Truyers C, Lowson D, et al

Patients who have been on stimulants in the past often require a higher phentermine dose to achieve meaningful appetite suppression, and in some cases outcomes are more limited