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The demand for GLP-1 receptor agonists has grown rapidly as these peptides prove their value in treating type 2 diabetes, obesity, and related metabolic disorders

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Speculatively, this could be due to different physiologic responds to food during day and evening, however the results could be biased by the fact that the hormonal response might be different in a fasted state than in a well fed state and furthermore our blood sample frequency are not high enough to surely capture the peak or nadir values after a meal

Instead, use different peptides for different areas or rotate between them