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Future investigations should implement standardized exercise prescriptions, longer follow-up, and preregistered multicenter designs to ensure methodological consistency and improve translational relevance

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2 Results and discussion 2.1 Preparation and characterization of Ru SA+AC nanozymes The Ru SA+AC nanozymes were synthesized by depositing Ru species and axially coordinated nitrogen atoms on g-C 3 N 4 by using a ligand-mediated polymerization confinement strategy (Fig

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