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Zepbound contains tirzepatide, a dual-acting medication that targets both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

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Both Type A and Type B deficiencies result in the loss of sulfite oxidase activity, also observed in isolated sulfite oxidase deficiency and characterized by severe neurologic abnormalities in affected patients

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Their anti-inflammatory action is essential, since low-grade inflammation is a key factor in the perpetuation of cardiovascular damage in patients with HFpEF, especially in the presence of obesity