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376 To block Notch signaling, -secretase inhibitors such as RO4929097 have been developed and have shown preclinical efficacy in reducing CSC populations and increasing sensitivity to standard therapies

Other pathways possibly associated with the parasitic processes were also analyzed, such as glutathione metabolism, one-carbon pool by folate, and cysteine and methionine metabolism

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Carefully sanitized in between clients as well as individual liners