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In 2006, for example, a new drug for treating rheumatoid arthritis passed animal safety tests but caused severe, life-threatening reactions when given to healthy human volunteers

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While semaglutide has a wide safety margin and overdose deaths are extremely rare, exceeding your planned injection or oral dose may result in acute gastrointestinal distress and metabolic complications

Symptoms treated effectively include sneezing, rhinorrhea, postnasal discharge, nasal pruritus, ocular pruritus, and tearing