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316 11751186 10.1124/jpet.105.094599 [DOI] [PubMed] [Google Scholar] Yang W

armament 8 3-inch

(2011) and related studies: Dose range : 1-10 g/kg body weight Frequency : Once daily or divided into twice-daily doses Route : Subcutaneous injection or direct injection into the injury site Duration : 7-28 days depending on injury severity and healing progression For a 70kg research subject, this translates to 70-700 g per dose

The effective concentration in cellular assays falls in the 10 to 100 nM window, with an EC50 of approximately 10 nM

[9] This study, which looked at EGT's interaction with epidermal keratinocytes , yielded several interesting findings