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You think youre large for your whole life and you look [back] and youre like, 'I was fit.' Yeah, I had big muscles

Matthew R Hayes, Heath D Schmidt, GLP-1 influences food and drug reward, Current Opinion in Behavioral Sciences, Volume 9, 2016, Pages 66-70, ISSN 2352-1546 Hjerpsted JB, Flint A, Brooks A, Axelsen MB, Kvist T, Blundell J

GLP-1 activation slows gastric emptying, reduces appetite, and stimulates insulin release

Most of these effects tend to lessen in frequency and intensity after your body adjusts to the medication, which typically happens within 4 to 8 weeks

Academic institutions, independent research organizations, or collaborative pharmaceutical initiatives could theoretically pursue these questions, though competitive dynamics make such studies unlikely in the near term