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Cardiac Ischemia Models (Porcine) Based on Crockford review (PMID: 17450230) of published cardiac studies: Dose: 6 mg Thymosin 4 per administration Administration: Intraperitoneal injection Frequency: Twice weekly for 4 weeks post-infarction Model: Coronary artery ligation with 90-minute ischemia followed by reperfusion Timing: First dose administered 6 hours post-reperfusion These protocols used full-length Thymosin 4

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