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It has not been evaluated well in humans, and its long-term effects are unknown

Four of the six genes investigated by quantitative RT-PCR were significantly up-regulated by Exendin-4 pre-conditioning, including Lactate dehydrogenase A ( Ldha ), Aldolase A ( Aldoa ), Phosphofructokinase ( Pfkp ) and Glucose-6-phosphate isomerase ( Gpi ) (Fig