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Even if you feel hungry, starting with smaller amounts prevents the discomfort that comes from overeating

It is known that the CV protection effect of GLP-1RAs have been proven through eight large-scale clinical studies, including Evaluation of LIXisenatide in Acute coronary syndrome (ELIXA) [66], LEADER [44], Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes (SUSTAIN)-6 [67], Exenatide Study of Cardiovascular Event Lowering (EXSCEL) [68], Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes) [69], Researching Cardiovascular Events with a Weekly INcretin in Diabetes (REWIND) [70], Peptide Innovation for Early Diabetes Treatment (PIONEER) 6 [67,71], and AMPLITUDE-O [51]

A registered dietitian can also help you navigate hunger and nutrition while on semaglutide

Retatrutide produces larger improvements in cardiovascular risk factors than approved medications

If youre interested in learning whether retatrutide may be appropriate for your health goals, the first step is to schedule a consultation with a qualified healthcare provider