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Description

The septic milieu itselfcharacterized by a cytokine storm and metabolic acidosisacts as a potent upstream disruptor of copper homeostasis, priming the heart for copper-dependent injury [175]

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Until real evidence says otherwise, the default assumption must be that such risks could exist

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After initial phase, we recommend monthly maintenance treatments for 3-6 months

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Sikiric et al., 1994

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GSTZ1 expression and chloride concentrations modulate sensitivity of cancer cells to dichloroacetate

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