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In a review of eight placebo-controlled studies published in 2022, three of them found that alpha lipoic acid reduced symptoms, but five found no significant difference
A similar report was presented last month at the Experimental Biology 2016 meeting in San Diego and published online in the FASEB Journal
More studies are necessary to confirm this, though
In some cases, further tests may be required to identify the underlying cause, such as the Schilling test (now rare) or the detection of antibodies against intrinsic factor or gastric parietal cells
Hirayama, K., Endo, K., Kawamura, S
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